Product Name:
Alumina Ceramic Blood Separation/Divert Valve
Product Material:
Biomedical Grade High-Purity Alumina Ceramic (Al₂O₃ ≥99.6%). For critical moving and sealing pairs such as valve cores and seats, Zirconia Toughened Alumina (ZTA) can be employed to enhance fracture toughness and wear life.
Material Characteristics:
Exceptional biocompatibility and hemocompatibility (complying with standards such as ISO 10993), Excellent chemical inertness (resistant to body fluids, blood, cleaning agents, and common disinfectants), High hardness and superior wear resistance, Very high dimensional stability, Good electrical insulation, Surface capable of achieving ultra-high smoothness (Ra < 0.1 µm) to reduce blood adhesion and turbulence, Material is pure and non-toxic with no risk of metal ion or organic leaching, Can withstand autoclave sterilization (high-temperature, high-pressure).
Application Fields:
Precise dispensing, switching, and mixing valves for blood/reagents in in-vitro diagnostic (IVD) equipment (e.g., biochemical analyzers, chemiluminescence immunoanalyzers, hematology analyzers); Ultra-pure water circuit control valves in hemodialysis equipment; Sterile fluid control valves in cell therapy or biopharmaceutical processes; Miniaturized integrated microfluidic valve chips in point-of-care testing (POCT) devices.
Application Industries:
Biomedical (In-vitro Diagnostics, Blood Purification, Biopharmaceuticals), Medical Device Manufacturing.
Processing Difficulties:
Machining valve cores or bodies with complex three-dimensional micron-scale flow channels, cross-holes, and cavity structures; Achieving sub-micron fitting accuracy and ultra-smooth sealing surfaces between the valve core and seat to enable zero-leakage and zero-residue switching; Ensuring ultra-high smoothness and defect-free inner walls of all flow channels to prevent blood adherence or thrombus formation; Achieving high-precision, biocompatible connections between valve components and polymer tubing or metal actuators; Meeting the most stringent cleanliness requirements for medical components regarding sterility, pyrogen-free, and particulate-free contamination.
Processing Flow:
Processing of medical-grade high-purity alumina powder → Precision Ceramic Injection Molding (CIM) or micromachining to form complex valve body green parts → Debinding and atmosphere-controlled precision sintering → Precision CNC grinding to establish datum surfaces and external profiles → Ultra-precision micromachining (micro-milling, grinding) to form internal flow channels and sealing surfaces → Ultrasonic-assisted precision polishing of all fluid-contact surfaces → Multiple rigorous cleaning steps (acid cleaning, ultrasonic, pure water rinse, plasma) and depyrogenation treatment → 100% dimensional, sealing, and functional testing → Biocompatibility sampling tests (e.g., hemolysis, cytotoxicity) → Drying and clean packaging in a high-class cleanroom (e.g., Class 100)
Delivery Period:
Standard design, biocompatibility-validated valve components: 80-120 days
Newly designed, structurally complex, or custom valves requiring full biosafety evaluation: 150-240 days
The Alumina Ceramic Blood Separation/Divert Valve is a core precision fluid control component in high-end in-vitro diagnostic and blood processing equipment, enabling precise, contamination-free transportation and switching of minute volumes of blood and reagents. In diagnostic and therapeutic processes crucial to life and health, every valve actuation must ensure zero cross-contamination, zero sample carryover, and the highest reliability. Alumina ceramic, with its inherent biosafety, comprehensive chemical stability, and achievable ultra-precision machinability, perfectly meets these stringent requirements. It not only provides a robust, inert, and absolutely clean channel for complex fluidic paths, but its ultra-smooth surfaces and nano-level sealing capability are also key to guaranteeing the accuracy and repeatability of test results, as well as the long-term maintenance-free operation of the equipment. It is an indispensable "heart" component in the fluidic systems of modern precision medical devices.
Key Features:
Absolute Biosafety and Sample Purity Assurance – The material passes rigorous biocompatibility testing, showing no adsorption or activation of blood components, and does not cause hemolysis or cytotoxicity. Its dense, non-porous structure completely prevents residue retention and permeation, ensuring that a previous sample does not contaminate a subsequent one (zero carryover), thereby laying the most fundamental foundation for the precision and reliability of diagnostic results.
Extraordinary Durability and Long-Term Operational Stability – The high hardness of alumina ceramic ensures minimal wear on the critical sealing surfaces of the valve core and seat pair, even after millions of high-frequency cycles, maintaining initial sealing performance over the long term. Its exceptional chemical resistance withstands repeated exposure to various cleaning agents and disinfectants. Combined with its tolerance for autoclave sterilization, this ensures no performance degradation throughout the valve's entire service life, meeting the stringent demands of medical equipment for long lifespan and low failure rates.
